Question

Reverse and suppressor mutations both result in wild phenotype. Thus they are both indistinguishable by any test performed on phenotype.

(a) True

(b) False

This question was addressed to me during an interview.

My doubt stems from DNA Mutation topic in division DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

Answer 1

The correct option is (b) False

For explanation I would say: Suppressor mutations are visible in the back cross as they are due to compensation and not a reversion to wild codon like reverse mutation. Thus, they can be distinguished by phenotypic study of back cross progeny.