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6, 4 PP are brought about by which type of mutagen?

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6, 4 PP are brought about by which type of mutagen?

(a) Methylase

(b) Phosphatase

(c) Radiation

(d) Base Analogue

This question was addressed to me during a job interview.

This interesting question is from Repair of DNA Damage: MMR, BER in chapter DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

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The correct option is (c) Radiation

Easiest explanation: 6,4 Pyrimidine photoproducts are formed when the DNA is exposed to strong radiation like UV or X-rays. These can be repaired by BER.

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