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Which of the following disease in humans is due to the error in MMR?

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Which of the following disease in humans is due to the error in MMR?

(a) Lynch syndrome

(b) Xeroderma Pigmentosum

(c) Cockyne’s syndrome

(d) Trichothio dystrophy

The question was posed to me in an internship interview.

I would like to ask this question from Repair of DNA Damage: MMR, BER in section DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

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The correct option is (a) Lynch syndrome

To elaborate: Lynch syndrome, also known as Hereditary Non-Poyposis Colon Cancer is due to the slippage of replicative machinery in the microsatellite region of the chromosomes where it encounters repetitive sequences. Option b and d are errors in NER.

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