Question

Absolute surface area is proportional to the dissolution rate of a drug.

(a) True

(b) False

I got this question by my school teacher while I was bunking the class.

Enquiry is from Drugs Absorption in division Absorption of Drugs of Drug Biotechnology

Answer 1

Correct option is (b) False

To explain I would say: Absolute surface area is not proportional to the Dissolution rate. Effective surface area is proportional to the dissolution rate. Absolute surface area is the total area of the solid surface of any particle and an effective surface area is the area of the solid surface exposed to the dissolution medium. Effective surface area is the area of the solid surface exposed to the dissolution medium.