Question

Which one of these is not a theory of Drug dissolution?

(a) Diffusion layer model

(b) Fick’s law of diffusion

(c) Penetration or surface renewal theory

(d) Interfacial barrier model

This question was posed to me in my homework.

This interesting question is from Physicochemical Factors Affecting Drug Absorption topic in portion Absorption of Drugs of Drug Biotechnology

Answer 1

Right answer is (b) Fick’s law of diffusion

To explain: Fick’s law of diffusion states that drug molecules diffuse from higher concentration to lower concentration until equilibrium is reached. Theories of drug dissolution are Diffusion layer model or Fil theory, Danckwert’s model or Penetration or surface renewal theory, Interfacial barrier model or Double barrier theory.