Question

In the equation G=Ki (Cs-Cb), what does G stands for______________

(a) Dissolution rate per unit area

(b) Effective interfacial transport constant

(c) Concentration of the solute

(d) Concentration of the impurity

The question was asked during an online interview.

Query is from Physicochemical Factors Affecting Drug Absorption in chapter Absorption of Drugs of Drug Biotechnology

Answer 1

Right choice is (a) Dissolution rate per unit area

The explanation is: According to the interfacial barrier model, an intermediate concentration exists at the interface which is a result of the solvation mechanism and is a function of solubility. Here in the equation G stands for dissolution rate per unit area, Ki stands for effective interfacial transport constant.