Question

What does the interfacial barrier model states?

(a) An intermediate concentration exists at the interface

(b) Turbulence in the dissolution medium exists at the solid/liquid interface

(c) Formation a thin film or layer at the solid-liquid interface

(d) Solutes passes easily through the interfaces

The question was asked in exam.

My query is from Physicochemical Factors Affecting Drug Absorption in section Absorption of Drugs of Drug Biotechnology

Answer 1

Right choice is (a) An intermediate concentration exists at the interface

Easy explanation: An intermediate layer exist at the interface of the solid and liquid layers. This intermediate layer holds and intermediate concentration at the interface which results is solvation mechanism. The theory does not talk about any turbulence, or presence of solutes.