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The total body water volume can be determined by using high molecular weight dyes.

(a) True

(b) False

The question was asked in a job interview.

My enquiry is from Drugs Distribution in section Distribution of Drugs of Drug Biotechnology

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Correct option is (b) False

For explanation I would say: The plasma volume can be determined by the use of high molecular weight dyes or substances which can easily get bind to plasma albumin. Total body water can be determined by heavy water or tritiated water and lipid soluble substances like antipyrine.

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