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Fat-free diet depresses cytochrome P-450 level.

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Fat-free diet depresses cytochrome P-450 level.

(a) True

(b) False

This question was posed to me in unit test.

The question is from Drugs Biotransformation in division Biotransformation of Drugs of Drug Biotechnology

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The correct option is (a) True

The explanation is: A fat-free diet decreases the phospholipid content. Phospholipids are important components of microsomes. When these become deficient, the cytochrome p-450 levels decrease.

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