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Which drugs bind to RBC membrane?

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Which drugs bind to RBC membrane?

(a) Pentobarbital

(b) Acetazolamide

(c) Imipramine

(d) Phenytoin

This question was addressed to me during an interview for a job.

This intriguing question comes from Plasma Protein Drug Binding topic in section Protein Binding of Drugs of Drug Biotechnology

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The correct option is (c) Imipramine

For explanation: The red blood cell comprises of 3 components each can bind to different kind of drugs. Haemoglobin, Carbonic anhydrase, and cell membrane. The cell membrane is reported to bind with chlorpromazine and imipramine.

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