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Only unbound or free drug is capable of being eliminated.

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Only unbound or free drug is capable of being eliminated.

(a) True

(b) False

I got this question by my school principal while I was bunking the class.

My question is from Factors Affecting Protein Drug Binding topic in chapter Protein Binding of Drugs of Drug Biotechnology

1 Answer

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Correct choice is (a) True

Easy explanation: Unbound or free drug is capable of being eliminated. Because the drug-protein complex cannot penetrate into the metabolizing organ. The large molecular size of the complex also prevents it from getting filtered through the glomerulus.

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