Question

This is the equation for the calculation of creatinine clearance. Which age group does the Clcr = (140 – Age) W / 72 * Scr formula belong to?

(a) 1-6 years

(b) 1-20 years

(c) Males above 20 years

(d) Females above 20 years

This question was addressed to me by my college professor while I was bunking the class.

This key question is from Pharmacokinetic topic in chapter Pharmacokinetic Drug Interactions & Basic Considerations of Drug Biotechnology

Answer 1

Correct answer is (c) Males above 20 years

For explanation: Calculation of creatinine clearance involves the determination of serum creatinine levels. Creatinine production varies with age, height and gender. The given equation is for males whose age is above 20 years. Clcr is creatinine clearance in ml/min, Scr is serum creatinine in mg%, H is height in cms, W is weight in kg, age is in years.