Question

An adult male with age 22 has height 240cm, weight 85kg, serum creatinine of 0.8mg will have ______________ creatinine clearance.

(a) 150 ml/min

(b) 160 ml/min

(c) 170.13 ml/min

(d) 174.131 ml/min

I had been asked this question in a national level competition.

I need to ask this question from Pharmacokinetic in portion Pharmacokinetic Drug Interactions & Basic Considerations of Drug Biotechnology

Answer 1

The correct choice is (d) 174.131 ml/min

Easiest explanation: For males of age above 20 years the equation for creatinine clearance is (140-age)*W / 72*Scr where, Clcr is creatinine clearance in ml/min, Scr is serum creatinine in mg%, H is height in cms, W is weight in kg, age is in years.