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Lipophilic drugs of molecular weight range 50-600 Dalton can pass the cell membrane to reach intracellular fluid.

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Lipophilic drugs of molecular weight range 50-600 Dalton can pass the cell membrane to reach intracellular fluid.

(a) True

(b) False

The question was asked in an international level competition.

This is a very interesting question from Drug Distribution in portion Distribution of Drugs of Drug Biotechnology

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The correct choice is (a) True

Best explanation: Drugs of size less than 50 Dalton can pass the cell membrane to reach intracellular fluid. Lipophilic drugs 50-600 Dalton and polar or ionized drugs of size less than 50 Dalton can pass the plasma membrane barrier.

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