Question

In Igf2 of human ______________ allele is expressed, and Igfr of mice __________ allele is expressed.

(a) Maternal, maternal

(b) Paternal, paternal

(c) Maternal, paternal

(d) Paternal, maternal

I got this question during a job interview.

I want to ask this question from Silencing and Genomic Imprinting in division Regulating Gene Expression in Eukaryotes of Cytogenetics

Answer 1

Correct choice is (d) Paternal, maternal

To explain I would say: The insulin like growth factor Igf for human shows that there only the paternal allele is expressed, but in its receptor, in case of mice the maternal allele is expressed. Thus both the alles must be present for proper function of the signal.