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Which of the following Cdk is resistant to Hct1?

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Which of the following Cdk is resistant to Hct1?

(a) G1

(b) G1-S

(c) Both G1 and G1-S

(d) G1, G1 S and S

I have been asked this question during an online exam.

This intriguing question comes from Cell Cycle Stages in section Cancer Biology & Methods in Cytogenetics of Cytogenetics

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Right choice is (c) Both G1 and G1-S

The best I can explain: The G1 Cdk is responsible for the re-initiation of the cell cycle, this is done by the process that G1 Cdk is resistant to Hct1, it transcribes G1-S. Thus even in G1 phase when the Hct1 concentration is high it can be activated. G1-S cyclin phosphorylates and inactivates Hct1.

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