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What is the antagonist for heroin?

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What is the antagonist for heroin?

(a) Naloxone

(b) Oxycodone

(c) Fentanyl

(d) Endomorphins

I had been asked this question during an internship interview.

The query is from Opioid Analgesics topic in chapter Local & General Anesthetics, Opioid Analgesics, Drug Addiction and Drug Abuse of Drug Biotechnology

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The correct answer is (a) Naloxone

Explanation: A heroin overdose is usually treated with an opioid antagonist, such as naloxone (Narcan) which has a high affinity for opioid receptors but does not activate them. Many death are caused due to the overdoses caused by interaction with depressant drugs like alcohol.

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