Question

What are the characteristics of the reservoir or membrane devices?

(a) The drug has a large therapeutic index

(b) Drug permeation rate is high

(c) Control drug release by partitioning the drug from the oil

(d) Administration of emulsions

I have been asked this question by my school teacher while I was bunking the class.

This interesting question is from Biopharmaceuticals in section Biopharmaceuticals of Drug Biotechnology

Answer 1

The correct option is (b) Drug permeation rate is high

Easiest explanation: These devices are used when the drug permeation through the stratum corneum is rapid than the rate of drug diffusion from the device. It is suitable for drugs which have low therapeutic indices. When applied on skin it shows rapid release at first and then zero order release as long as the solution inside the reservoir is saturated.