Question

Comparing two-dimensional gel images from various experiments can sometimes pose a challenge because the gels, unlike DNA microarrays, may shrink or warp.

(a) True

(b) False

The question was asked by my college professor while I was bunking the class.

Origin of the question is Technology of Protein Expression Analysis topic in section Functional Genomics & Proteomics of Bioinformatics

Answer 1

The correct option is (a) True

For explanation: This requires the software programs to be able to stretch or maneuver one of the gels relative to the other to find a common geometry. When the reference spots are aligned properly, the rest of the spots can be subsequently compared automatically.