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Electrospray ionization MS and matrix-assisted laser desorption ionization (MALDI) MS only differ in the ionization procedure used.

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Electrospray ionization MS and matrix-assisted laser desorption ionization (MALDI) MS only differ in the ionization procedure used.

(a) True

(b) False

The question was asked in homework.

My enquiry is from Technology of Protein Expression Analysis in portion Functional Genomics & Proteomics of Bioinformatics

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Correct option is (a) True

Easy explanation: In MALDI-MS, for example, the peptides are charged with positive ions and forced through an analyzing tube with a magnetic field. Peptides are analyzed in the gas phase. Because smaller peptides are deflected more than larger ones in a magnetic field, the peptide fragments can be separated according to molecular mass and charges. A detector generates a spectrum that displays ion intensity as a function of the mass-to-charge ratio.

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