Question

In Predicting Interactions Based on Gene Neighbors if a certain gene linkage is found to be indeed conserved across divergent genomes, it can be used as a strong indicator of formation of an operon that encodes proteins that are functionally and even physically coupled.

(a) True

(b) False

This question was posed to me in a national level competition.

Query is from Protein Interactions in division Functional Genomics & Proteomics of Bioinformatics

Answer 1

The correct choice is (a) True

The best I can explain: This rule of predicting protein–protein interactions holds up for most prokaryotic genomes. For eukaryotic genomes, gene order may be a less potent predictor of protein interactions than a tight co-regulation for gene expression.