Question

For proteins in stable complexes the average sequence identity is 46%, while for proteins in transient interactions it is 41%.

(a) True

(b) False

This question was addressed to me in my homework.

My question comes from Protein in section Global Approaches for Studying Protein – Protein Interactions of Bioinformatics

Answer 1

Right choice is (a) True

For explanation: (Proteins not known to be involved in any type of interaction have an average sequence identity of 38 %) One of the main reasons for this is the surface area involved in interfaces of stable complexes which is larger than in transient complexes. Sequence divergence may be slower in order to conserve these extensive interfaces.