Question

You radiate a stock of E. Coli with UV rays and another stock is irradiated as control. The 1st stock is seen to be more resistant to alkylating agents. Which gene is expected to be triggered by this UV?

(a) AlK B

(b) Guanine methyl transferase

(c) MTHF poly Glu

(d) RUV

The question was posed to me during an interview for a job.

This question is from Repair of DNA Damage: NER, Direct Reversal topic in division DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

Answer 1

Correct choice is (b) Guanine methyl transferase

Explanation: While Alk B is also a de-methylating agent, but in E. coli the UV inducible de-alkylating agent is 8-oxo guanine methyl transferase.