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The bulky lesions in GG-NER is detected by ___________

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in Cytogenetics by (679k points)
The bulky lesions in GG-NER is detected by ___________

(a) XPA

(b) XPD

(c) XPC

(d) XPG

This question was addressed to me during a job interview.

I'm obligated to ask this question of Repair of DNA Damage: NER, Direct Reversal in chapter DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

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The correct option is (c) XPC

Easy explanation: XPC in association with the hHR23B is responsible for recognizing the bulky lesions and attaching the XPB and XPD.

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