Question

The enzymes are divided into two categories, these are _______ and ____________

(a) Acidic drug metabolizing and basic drug metabolizing

(b) Present in the liver and not present in the liver

(c) Microsomal and non-microsomal

(d) There is no such division

This question was addressed to me at a job interview.

This intriguing question comes from Drugs Biotransformation topic in section Biotransformation of Drugs of Drug Biotechnology

Answer 1

Right option is (c) Microsomal and non-microsomal

To explain I would say: The enzymes are divided into 2 categories namely microsomal and non-microsomal. Microsomal enzymes catalyse the majority of the drug biotransformation reactions. The large variety of microsomal enzymes catalyse a number of oxidative, reductive and hydrolytic reactions.