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What is the equation of bioavailable fraction?

(a) 1/Bioavailable dose

(b) 1/Administered dose

(c) Bioavailable dose/Administered dose

(d) Administered dose/Bioavailable dose

This question was posed to me by my school teacher while I was bunking the class.

This interesting question is from Bioavailability in portion Compartment Modelling, Non Linear Pharmacokinetics, Bioavailability and Bioequivalence of Drug Biotechnology

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Correct answer is (c) Bioavailable dose/Administered dose

Explanation: The amount of drug that reaches the systemic circulation is known as systemic bioavailability. The bioavailable fraction F refers to the fraction of administered dose that enters the systemic circulation after drug administration. The equation is F = Bioavailable dose/Administered dose.

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