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Which of the following factors for protein drug binding is a drug interaction factor?

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Which of the following factors for protein drug binding is a drug interaction factor?

(a) Competition between drugs for the binding site

(b) Age

(c) Physicochemical characteristics of a drug

(d) Physicochemical characteristics of the protein or binding agent

This question was posed to me at a job interview.

My question is from Factors Affecting Protein Drug Binding topic in chapter Protein Binding of Drugs of Drug Biotechnology

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Correct answer is (a) Competition between drugs for the binding site

Explanation: Physicochemical interaction is not a drug interaction factor. Competition between the drug and the binding site and competition between drug and other normal body constituents, allosteric changes in protein molecule all these factors are related to drug interaction with the protein. Age is a patient-related factor.

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