Question

Which one of the following factors related to protein-drug binding is not related to drugs?

(a) Physicochemical characteristics of a drug

(b) The concentration of the drug in the body

(c) The affinity of the drug for binding

(d) Number of binding sites on the binding agent

I had been asked this question in an international level competition.

This interesting question is from Factors Affecting Protein Drug Binding in division Protein Binding of Drugs of Drug Biotechnology

Answer 1

The correct option is (d) Number of binding sites on the binding agent

For explanation: There are many factors affecting protein-drug binding. The factors related to the drug, are physicochemical characteristics of a drug, concentration of the drug in the body, affinity of the drug for binding. A number of binding sites on the binding agent are related to the protein and other binding components.