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Which of the following are natural opiates?

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Which of the following are natural opiates?

(a) Codeine

(b) Oxycodone

(c) Fentanyl

(d) Endomorphins

I have been asked this question in an interview for job.

This interesting question is from Opioid Analgesics topic in section Local & General Anesthetics, Opioid Analgesics, Drug Addiction and Drug Abuse of Drug Biotechnology

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The correct choice is (a) Codeine

The best I can explain: Natural opiates are alkaloid contained in the resin of the opium poppy including morphine and codeine. Semi-synthetic opiates are created from natural opiates such as hydromorphone, oxycodone, and diacetylmorphine. Fully synthetic opioids are such as fentanyl, methadone, etc.

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