Question

Which of the following are endogenous opioid peptides?

(a) Codeine

(b) Oxycodone

(c) Fentanyl

(d) Endomorphins

This question was addressed to me in examination.

I'm obligated to ask this question of Opioid Analgesics in division Local & General Anesthetics, Opioid Analgesics, Drug Addiction and Drug Abuse of Drug Biotechnology

Answer 1

Right option is (d) Endomorphins

To elaborate: Endogenous opioid peptides are produced naturally in the body, such as endorphins, Endomorphins, etc. Heroin and morphine exert their effects by mimicking naturally occurring substances, called endogenous opioid peptides or endorphins. Natural opiates are alkaloid contained in the resin of the opium poppy including morphine and codeine. Semi-synthetic opiates are created from natural opiates such as hydromorphone, oxycodone, and diacetylmorphine. Fully synthetic opioids are such as fentanyl, methadone, etc.