Question

What is the characteristics of mucoadhesive systems?

(a) Release the drug along the entire length of GIT

(b) Prolonged their residence in the GIT and release

(c) Usage of bio adhesive polymer

(d) Use of high or low density pellets

I had been asked this question during a job interview.

I'm obligated to ask this question of Biopharmaceuticals topic in chapter Biopharmaceuticals of Drug Biotechnology

Answer 1

Right answer is (c) Usage of bio adhesive polymer

Best explanation: Bio adhesive polymers when they are used as a cross linked polyacrilic acid and are incorporated in a tablet, it allows it to adhere to the gastric mucosa or epithelium. Such a system continuously releases a fraction of drug into the intestine over prolonged period of time increasing the pharmaco therapeutic time.