Question

Which of the following is false in regarding reservoir devices?

(a) These devices are used when the drug permeation rate is rapid

(b) The release of the drug is controlled

(c) Suitable for low therapeutic indices

(d) The drug is contained in a powder form floating on liquid

I have been asked this question in a national level competition.

Query is from Biopharmaceuticals topic in division Biopharmaceuticals of Drug Biotechnology

Answer 1

Right answer is (d) The drug is contained in a powder form floating on liquid

The explanation: The drug is contained in a reservoir as a suspension liquid or gel carrier. The thin polymeric membrane is made up of olefinic polymers or PVC. When applied on skin it shows rapid release at first and then zero order release as long as the solution inside the reservoir is saturated.