Question

Coiled coils are super helical structures involving two to more interacting α-helices from the same or different proteins.

(a) True

(b) False

The question was asked during an interview for a job.

My question comes from Coiled Coil Prediction in section Secondary Structure Prediction of Bioinformatics

Answer 1

Right answer is (a) True

To explain: The individual α-helices twist and wind around each other to form a coiled bundle structure. The coiled coil conformation is important in facilitating inter- or intra protein interactions. Proteins possessing these structural domains are often involved in transcription regulation or in the maintenance of cytoskeletal integrity.