Question

What type of drug administration will have the shown compartment model?

(a) Intravenous administration

(b) Oral administration

(c) Rectal administration

(d) Sublingual administration

This question was posed to me by my school principal while I was bunking the class.

My enquiry is from Pharmacokinetic Models in portion Pharmacokinetic Drug Interactions & Basic Considerations of Drug Biotechnology

Answer 1

Correct option is (a) Intravenous administration

For explanation: There is no arrow entering the 1^st compartment itself, this means whatever the administration is it directly goes into the blood. In intravenous administration, the blood is considered to be the 1^st compartment. Since one single compartment is shown it will be intravenous administration. K10 is the first order elimination rate constant.