Question

Which of the following is not a characteristic of the caternary compartment model?

(a) It gives a visual representation of various rate processes in drug disposition

(b) It shows how many rate constants are necessary

(c) Compartments and parameters bear a relationship with physiologic functions

(d) Useful in predicting drug

The question was posed to me at a job interview.

Enquiry is from Pharmacokinetic Models in chapter Pharmacokinetic Drug Interactions & Basic Considerations of Drug Biotechnology

Answer 1

Right option is (c) Compartments and parameters bear a relationship with physiologic functions

To explain: In the caternary model, compartments and parameters are not in a relationship with the physiological functions of the species. This is a disadvantage of the caternary model. Caternary model gives a visual representation of various rate processes, it shows how many rate constants are necessary, etc.