Question

Multiple dose study is better since we can understand the peak, valley, drug blood levels, etc.

(a) True

(b) False

I had been asked this question in a national level competition.

My doubt is from Bioavailability in portion Compartment Modelling, Non Linear Pharmacokinetics, Bioavailability and Bioequivalence of Drug Biotechnology

Answer 1

The correct answer is (a) True

For explanation: Multiple dose study is difficult to control since it exposes the subject to a higher level of drug which is dangerous sometimes. This method is very tedious and time-consuming. The advantages of such method are accurately reflected how the drug should be used, easy to predict peak and valley of a drug, can be ethically performed on the patient, better evaluation of the performance of controlled release formulation is possible.