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Which metals get accumulated in the kidney?

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Which metals get accumulated in the kidney?

(a) Mercury, cadmium, lead

(b) Mercury, cadmium, iron

(c) Mercury, lanthanum, lead

(d) Mercury, cadmium, fluoride ions

I have been asked this question during an interview.

This question is from Tissue Binding of Drugs topic in chapter Protein Binding of Drugs of Drug Biotechnology

1 Answer

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Right choice is (a) Mercury, cadmium, lead

Best explanation: Metallothionin, is a protein present in kidneys. This protein tends to bind to heavy metals such as mercury, cadmium, lead. Resulting in their accumulation in kidney and toxicity.

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