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Which drugs deposit in hair shafts?

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Which drugs deposit in hair shafts?

(a) Arsenicals

(b) Tetracycline

(c) Halogenated hydrocarbons

(d) Lipophilic drug

The question was posed to me in a job interview.

I would like to ask this question from Tissue Binding of Drugs topic in division Protein Binding of Drugs of Drug Biotechnology

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The correct option is (a) Arsenicals

For explanation I would say: Arsenicals, chloroquine, phenothiazines are reported to deposit in hair shaft. Tetracycline binds to bones and teeths. Lipophilic drugs accumulate in adipose tissues. Epoxides of number of Halogenated hydrocarbon and paracetamol bind irreversibly to the liver tissues resulting in hepatotoxicity.

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